Parallel Screening for Rapid Identification of Orthogonal Bioluminescent Tools
نویسندگان
چکیده
منابع مشابه
Parallel Screening for Rapid Identification of Orthogonal Bioluminescent Tools
Bioluminescence imaging with luciferase enzymes and luciferin small molecules is a well-established technique for tracking cells and other biological features in rodent models. Despite its popularity, bioluminescence has long been hindered by a lack of distinguishable probes. Here we present a method to rapidly identify new substrate-selective luciferases for multicomponent imaging. Our strateg...
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ژورنال
عنوان ژورنال: ACS Central Science
سال: 2017
ISSN: 2374-7943,2374-7951
DOI: 10.1021/acscentsci.7b00394